FAQs - Clinicians


Always refer to the Instructions for Use (IFU) prior to any application of the NATROX® Oxygen Wound Therapy

The wound is smaller than the NATROX® oxygen delivery system (ODS) can I cut the ODS?

It’s best not to cut the NATROX® ODS as it has been designed to diffuse oxygen evenly across the whole wound bed.

Is it alright to put the NATROX® ODS on intact skin?

It is safe to apply the NATROX® ODS on healthy peri-wound skin.

If the peri-wound skin isn’t healthy, can I still overlap the NATROX® ODS onto it?

Yes, a barrier cream should be applied to the unhealthy peri-wound skin to protect from further damage

The wound has increased in size since commencing the NATROX® system, should I stop the therapy?

No, its not unusual for the wound to increase in size initially. As long as there are no clinical signs of infection continue with the NATROX® system.

If the wound is not showing any signs of improvement within 2 weeks should I stop therapy?

No, as previously stated its not abnormal for the wound to increase in size initially.

If the wound has been present for years, will the NATROX® system still work?

Yes, very chronic wounds can still respond and benefit from the NATROX® system.

Can you use the NATROX® system with Negative Pressure Wound Therapy (NPWT)?

There is no evidence to-date that supports combining both therapies.

Can the NATROX® system be applied if a wound has slough or necrotic tissue in the wound bed?

We would always advise to get the wound as clean as possible before applying the NATROX® system.

Can you start NATROX® whilst the patient is being treated with antibiotics?

Yes, however if the wound is still showing signs of clinical infection then wait until it has settled.

Can the NATROX® system stimulate bacterial growth in a wound?

It is possible for aerobic bacteria, but unlikely.

Can I stop using the NATROX® system once the wound has started to improve?

We would advise you continue with the NATROX® system until complete wound closure is achieved.

Pain reduction is often reported by patients, is there an explanation for this?

Yes, nerve endings are very sensitive to reduced levels of oxygen. Therefore increasing oxygen levels can significantly aid pain relief.

Can you explain the process of how NATROX® generates oxygen?

Moisture in the air reacts with the NATROX® cell, splitting it into its component parts, one of which is oxygen.

How much oxygen does the wound need?

Air consists of 21% oxygen; in normal circumstances tissue O2 levels can never be higher than this. In reality O2 levels are likely to be less, due to underlying disease processes.

Does Inotec AMD recommend any specific dressings to use with NATROX®?

No, the choice of dressing is down to clinical preference, however semi-occlusive dressings have enhanced properties for retaining oxygen levels.

Occasionally a translucent yellow covering can develop on the wound after using the NATROX® system for 2-3 weeks, is this harmful?

This is not an uncommon observation, however its presence is not associated with any delay in healing.

Can you use the NATROX® system on patients with multiple wounds?

Yes, although the location and size of the wounds will dictate the best application method.


Oxygen is critical to many of the processes
required in wound healing. NATROX® Oxygen
Wound Therapy allows you to prescribe topical
oxygen in a very simple, safe and extremely
convenient way directly to the wound bed.


NATROX® Oxygen Wound Therapy is a small
portable device about the size of a mobile
phone. Its function is to produce concentrated
oxygen from the surrounding air, and pass this
down a thin flexible tube directly to a wound
that is failing to progress as expected.